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Featured image for Panama Canal: Miami to Los Angeles aboard Brilliant Lady
Cruise
Panama Canal: Miami to Los Angeles aboard Brilliant Lady
Board in Port of Miami, Florida, USA on Friday, March 26, 2027 for a Panama Canal itinerary visiting Miami, Florida, USA, Cartagena, Colombia, Colón, Panama, Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Cabo San Lucas, Mexico, and Los Angeles, California, USA, with recent cabin pricing captured as low as $3,488 per cabin for two sailors.
As low as $3,488 per cabin
Check Availability & Book →
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Rachael Roberts
SOLD AND SERVICED BY
Rachael Roberts
LAST UPDATED ON
June 12, 2026

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Departure

  • Port of Miami, Florida, USA

Destination

  • Port of Los Angeles, California, USA

Voyage at a glance

16-night Caribbean sailing aboard Brilliant Lady.

ShipBrilliant Lady
Sailing datesFriday, March 26, 2027 – Sunday, April 11, 2027
RoutePort of Miami, Florida, USA → Port of Los Angeles, California, USA
Featured stopsCartagena, Colombia · Colón, Panama · Puntarenas, Costa Rica · Puerto Quetzal, Guatemala · Cabo San Lucas, Mexico
Recently found from$3,488 per cabin for two sailors

This iconic one-way voyage from Miami to Los Angeles visits Cartagena, Colon, Puntarenas, Puerto Quetzal, and Cabo San Lucas, with an awe-inspiring trip through the Panama Canal on the way. After you make your way through the famed canal, enjoy the pristine white sand beaches of Cabo San Lucas, a tropical paradise you'll remember long after you've disembarked.

Itinerary Overview

Day 1 – Friday, March 26, 2027 · Miami, Florida, USA

Departure from Miami, Florida, USA

Departs 5:00 PM

Board in Miami, Florida, USA, settle into the ship, and get ready for sailaway around 5:00 PM.

  • Boarding
  • Dining
  • Entertainment
Day 2 – Saturday · Sailing

Sailing

Enjoy a full day of sailing with time for dining, entertainment, ocean views, and relaxing onboard.

  • Sailing
  • Dining
  • Entertainment
  • Spa & Fitness
Day 3 – Sunday · Sailing

Sailing

Enjoy a full day of sailing with time for dining, entertainment, ocean views, and relaxing onboard.

  • Sailing
  • Dining
  • Entertainment
  • Spa & Fitness
Day 4 – Monday · Cartagena, Colombia

Port day: Cartagena, Colombia

9:00 AM – 5:00 PM

Arrive in Cartagena, Colombia around 9:00 AM and enjoy the port before the scheduled 5:00 PM departure. With mystical museums, five-star restaurants, and white sand beaches, in Cartagena there's something for everyone.

  • Excursions
  • Beach Day
  • Food
  • Shopping
Day 5 – Tuesday · Colón, Panama

Port day: Colón, Panama

10:00 AM – 7:00 PM

Arrive in Colón, Panama around 10:00 AM and enjoy the port before the scheduled 7:00 PM departure. The entry to the Panama Canal, indulge in self-care on a white sand beach or hike through one of the nearby lush rainforests.

  • Scenic Cruising
  • Photography
  • Excursions
Day 6 – Wednesday · Sailing

Scenic cruising: Panama Canal (Cruising), Panama

Experience scenic cruising near Panama Canal (Cruising), Panama. The canal our lady ship was built for gives you time to observe diverse species sailing with you or in the opposite direction.

  • Scenic Cruising
  • Photography
  • Excursions
Day 7 – Thursday · Sailing

Sailing

Enjoy a full day of sailing with time for dining, entertainment, ocean views, and relaxing onboard.

  • Sailing
  • Dining
  • Entertainment
  • Spa & Fitness
Day 8 – Friday · Puntarenas, Costa Rica

Port day: Puntarenas, Costa Rica

9:00 AM – 6:00 PM

Arrive in Puntarenas, Costa Rica around 9:00 AM and enjoy the port before the scheduled 6:00 PM departure. Explore the verdant lands and take a dip in the waterfalls that are seemingly at every turn in this picturesque paradise.

  • Excursions
  • Food
  • Shopping
Day 9 – Saturday · Sailing

Sailing

Enjoy a full day of sailing with time for dining, entertainment, ocean views, and relaxing onboard.

  • Sailing
  • Dining
  • Entertainment
  • Spa & Fitness
Day 10 – Sunday · Puerto Quetzal, Guatemala

Port day: Puerto Quetzal, Guatemala

8:00 AM – 5:00 PM

Arrive in Puerto Quetzal, Guatemala around 8:00 AM and enjoy the port before the scheduled 5:00 PM departure. One of the busiest ports in the country, Puerto Quetzal is the gateway to all things Guatemala.

  • Excursions
  • Food
  • Shopping
Day 11 – Monday · Sailing

Sailing

Enjoy a full day of sailing with time for dining, entertainment, ocean views, and relaxing onboard.

  • Sailing
  • Dining
  • Entertainment
  • Spa & Fitness
Day 12 – Tuesday · Sailing

Sailing

Enjoy a full day of sailing with time for dining, entertainment, ocean views, and relaxing onboard.

  • Sailing
  • Dining
  • Entertainment
  • Spa & Fitness
Day 13 – Wednesday · Sailing

Sailing

Enjoy a full day of sailing with time for dining, entertainment, ocean views, and relaxing onboard.

  • Sailing
  • Dining
  • Entertainment
  • Spa & Fitness
Day 14 – Thursday · Cabo San Lucas, Mexico

Port day: Cabo San Lucas, Mexico

8:00 AM – 5:00 PM

Arrive in Cabo San Lucas, Mexico around 8:00 AM and enjoy the port before the scheduled 5:00 PM departure. Spend the day on the notoriously beautiful beaches, go on an adventure via zipline, glass bottom funicular, ATV or snorkel.

  • Excursions
  • Beach Day
  • Food
  • Shopping
  • Tender Port
Day 15 – Friday · Sailing

Sailing

Enjoy a full day of sailing with time for dining, entertainment, ocean views, and relaxing onboard.

  • Sailing
  • Dining
  • Entertainment
  • Spa & Fitness
Day 16 – Saturday · Sailing

Sailing

Enjoy a full day of sailing with time for dining, entertainment, ocean views, and relaxing onboard.

  • Sailing
  • Dining
  • Entertainment
  • Spa & Fitness
Day 17 – Sunday, April 11, 2027 · Los Angeles, California, USA

Arrival in Los Angeles, California, USA

Arrives 6:30 AM

Arrive back in Los Angeles, California, USA around 6:30 AM for debarkation. Please allow up to an hour for the Gangway to open to disembark

  • Boarding
  • Dining
  • Entertainment

Highlights

Step aboard Brilliant Lady in Port of Miami, Florida, USA for an exciting 16-night Panama Canal cruise visiting Miami, Florida, USA, Cartagena, Colombia, Colón, Panama, Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Cabo San Lucas, Mexico, and Los Angeles, California, USA.
This itinerary blends the easy anticipation of sailaway with destination days made for photos, great meals, and unhurried exploring. Expect polished shipboard style, coastal energy, and the kind of pacing that makes the trip feel effortless.
Recent cabin pricing was captured as low as $3,488 per cabin for two sailors, subject to live availability.
Recently found pricing

Cabin pricing snapshot

Recent cabin prices we found for this sailing. Pricing is shown per cabin for two sailors and may change at any time.

Cabin Types
  • InsiderRecently found from $3,488 per cabin
    Limited-time savings shown at last check: 31% off
  • Sea ViewRecently found from $4,448 per cabin
    Limited-time savings shown at last check: 35% off
  • Sea TerraceRecently found from $5,408 per cabin
    Limited-time savings shown at last check: 40% off
  • Rockstar QuartersRecently found from $18,208 per cabin
  • Mega Rockstar QuartersRecently found from $30,560 per cabin

Final taxes, fees, promotions, or availability can change.

Additional Information

This offer availability and pricing is constantly subject to change. We suggest to book this now.

Other sailings to consider:

Tags

allcruisespanama-canalbrilliant-ladymar2027