22-Night South America Cruise on Seven Seas Mariner
South America is huge, with scenic wonders that would impress even the most jaded traveler, cosmopolitan cities and native villages, snow-capped mountains, deserts and lush rain forests, miles of sandy beaches and areas so isolated a visitor feels swept back in time. There are many options to cruising South America, and there is no better way to explore this vast continent than on a cruise vacation.
Book with a professional travel advisor and you may unlock more than what appears in a standard online search. Depending on the supplier and trip, your advisor may have access to preferred or agency-negotiated group rates, special promotions, upgrades, onboard or resort credits, and other added-value benefits that are not always available through direct booking.
During our consultation, we may ask for a few details—such as your country or state of residence, ZIP code, age eligibility, military status, past-guest history, or loyalty memberships. These details can help us identify fares and benefits you may qualify for and compare them against publicly available options.
Not every offer applies to every traveler, and availability varies by supplier, destination, sailing, travel dates, and eligibility. But the more we know about your trip and the qualifications that may apply to you, the more thoroughly we can search for opportunities to enhance your vacation and help you secure the best available overall value not just the first price you see online.
Recent price found was as low as: $19,099 per person. Port charges, taxes, and fees of $2,502 USD included
Itinerary Overview
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Day 1 · Miami, Florida
Miami, Florida
Depart 5:00 pm
Discover the cosmopolitan beauty of Miami along Florida's fabled Gold Coast. Stroll through carefully preserved Art Deco neighborhoods and witness the trendy lifestyle that is South Beach. Enjoy open-air shopping in the Bayside Marketplace and shop for a bite to eat in Coconut Grove, with its harborside cafes and quaint, artistic settings.
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Day 2 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 3 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 4 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 5 · Bridgetown, Barbados
Bridgetown, Barbados
Arrive 9:00 am · Depart 5:00 pm
The Bajan British accent is very distinctive, reflecting both the Scepter'd Isle and the lovely one they live on. Barbados still has lovely parish churches, great manor houses and a proper Trafalgar Square along with white-sugar beaches and waving fields of cane.
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Day 6 · Port of Spain, Trinidad
Port of Spain, Trinidad
Arrive 7:00 am · Depart 4:00 pm
Steel drums and calypso were born here. Nature lovers will delight in the Asa Wright Nature Center and the Caroni Bird Sanctuary, two of the Caribbean's best known conservation centers.
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Day 7 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 8 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 9 · CRUISING THE AMAZON RIVER
CRUISING THE AMAZON RIVER
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Day 10 · Santarem, Brazil
Santarem, Brazil
Arrive 9:00 am · Depart 6:00 pm
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Day 11 · Boca da Valeria, Brazil
Boca da Valeria, Brazil
Arrive 7:00 am · Depart 3:00 pm
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Day 12 · Manaus, Brazil
Manaus, Brazil
Arrive 9:00 am · Depart 5:00 pm
A cultural outpost in the heart of the Amazon rainforest, Manaus was famous for the extravagant lifestyle and architecture of the 19th century rubber barons who made their fortunes here. The renovated opera house stands as an opulent testament to their vast wealth.
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Day 13 · Parintins, Brazil
Parintins, Brazil
Arrive 11:00 am · Depart 7:00 pm
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Day 14 · Alter do Chao, Brazil
Alter do Chao, Brazil
Arrive 7:00 am · Depart 3:00 pm
Turning out of the muddy Amazon, you will cruise into the blue Rio Tapajos, to anchor off the village of Alter do Chao. Here you can tour the Center for Preservation of Indigenous Arts, with displays on the lifestyles of local tribes. Or cross to a white sand beach for a refreshing swim in the clear river waters.
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Day 15 · CRUISING THE AMAZON RIVER
CRUISING THE AMAZON RIVER
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Day 16 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 17 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 18 · St. Georges, Grenada, West Indies
St. Georges, Grenada, West Indies
Arrive 11:30 am · Depart 8:30 pm
Called the "Spice Island" for its abundance of cinnamon and nutmeg, still sold at the waterfront market, Grenada is spicy in many other ways. St. George's has historic buildings in brick and mellow stone, and one of the loveliest harbors in the Caribbean. The coastline is full of secluded coves, while the mountainous interior is rich in rainforests and frothy rivers.
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Day 19 · CRUISING THE CARIBBEAN SEA
CRUISING THE CARIBBEAN SEA
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Day 20 · San Juan, Puerto Rico
San Juan, Puerto Rico
Arrive 7:00 am · Depart 8:00 pm
The fortress of El Morro guards the harbor against long-gone Sir Francis Drake and his British privateers. The colorful streets of Old San Juan retain the Latin flavor of its seafaring past, when this was the heart of the Spanish Main. Sample the fiery rum made here, or indulge in an icy treat made from fresh tropical fruit and enjoy the Caribbean atmosphere.
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Day 21 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 22 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 23 · Miami, Florida
Miami, Florida
Arrive 6:00 am
Discover the cosmopolitan beauty of Miami along Florida's fabled Gold Coast. Stroll through carefully preserved Art Deco neighborhoods and witness the trendy lifestyle that is South Beach. Enjoy open-air shopping in the Bayside Marketplace and shop for a bite to eat in Coconut Grove, with its harborside cafes and quaint, artistic settings.
Route Illustration - Actual route may differ
Highlights
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Sail aboard Seven Seas Mariner.
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Travel from 2026-11-09 through 2026-12-01.
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Visit Miami, Florida, Bridgetown, Barbados, Port of Spain, Trinidad, Santarem, Brazil, Boca da Valeria, Brazil, Manaus, Brazil, Parintins, Brazil, Alter do Chao, Brazil, St. Georges, Grenada, West Indies, San Juan, Puerto Rico.
Recently found pricing
Cabin pricing snapshot
Recent cabin prices we found for this sailing. Pricing is shown per person and may change at any time.
Cabin Types
Inside
Not currently available — cabin inventory may change.
Oceanview
Not currently available — cabin inventory may change.
Balcony
Not currently available — cabin inventory may change.
SuiteRecently found from $19,099 per person
Port charges, taxes, and fees of $2,502 USD included
Final taxes, fees, promotions, or availability can change.
Additional Information
Price, availability, taxes, fees, promotions, occupancy requirements, and final cabin availability can change until booked. When you book travel through a professional travel advisor, suppliers often provide exclusive value-adds, upgrades, and promotions that are unavailable when booking directly online. These unadvertised or agency-exclusive perks vary by vendor and destination.
Gallery
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Route Illustration - Actual route may differ
Tags
allcruiseSouth AmericaRegent Seven Seas CruisesSeven Seas MarinerMiami, Florida