16-Night Panama Canal Cruise on Seven Seas Grandeur
Slice through Central America via the most famous canal in the world. With more than 900 species of birds, 10,000 species of plants, 1,350 plants and animals indigenous to the country and more species of mammals and amphibians than any other Central American country, Panama has one of the richest tropical environments on earth. Follow the footsteps of the conquistadors and immerse yourself in Panama's rich ecological and cultural diversity.
Book with a professional travel advisor and you may unlock more than what appears in a standard online search. Depending on the supplier and trip, your advisor may have access to preferred or agency-negotiated group rates, special promotions, upgrades, onboard or resort credits, and other added-value benefits that are not always available through direct booking.
During our consultation, we may ask for a few details—such as your country or state of residence, ZIP code, age eligibility, military status, past-guest history, or loyalty memberships. These details can help us identify fares and benefits you may qualify for and compare them against publicly available options.
Not every offer applies to every traveler, and availability varies by supplier, destination, sailing, travel dates, and eligibility. But the more we know about your trip and the qualifications that may apply to you, the more thoroughly we can search for opportunities to enhance your vacation and help you secure the best available overall value not just the first price you see online.
Recent price found was as low as: $16,949 per person. Port charges, taxes, and fees of $1,796 USD included
Itinerary Overview
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Day 1 · Miami, Florida
Miami, Florida
Depart 5:00 pm
Discover the cosmopolitan beauty of Miami along Florida's fabled Gold Coast. Stroll through carefully preserved Art Deco neighborhoods and witness the trendy lifestyle that is South Beach. Enjoy open-air shopping in the Bayside Marketplace and shop for a bite to eat in Coconut Grove, with its harborside cafes and quaint, artistic settings.
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Day 2 · CRUISING THE STRAITS OF FLORIDA
CRUISING THE STRAITS OF FLORIDA
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Day 3 · Georgetown, Grand Cayman, Cayman Islands
Georgetown, Grand Cayman, Cayman Islands
Arrive 9:00 am · Depart 4:00 pm
Survey the neatly shuttered shops for bargains, or the twisted rock formations known as "Hell." But there's nothing hellish about the white-sand heaven of Seven Mile Beach. Sample the rum distilled here and be sure to visit the world's only sea turtle farm.
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Day 4 · CRUISING THE CARIBBEAN SEA
CRUISING THE CARIBBEAN SEA
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Day 5 · Cartagena, Spain
Cartagena, Spain
Arrive 7:00 am · Depart 2:00 pm
...The weather almost never becomes too hot or uncomfortable, and the sights and smells of the land are marvelous...It is also Spain's main naval base...The landscaped squares of Cartagena are so magnificent that you can spend hours just sitting and looking...The buildings and religious structures of the city add to its wonderful culture, and a walking tour of Cartagena is great fun.
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Day 6 · PANAMA CANAL TRANSIT
PANAMA CANAL TRANSIT
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Day 7 · CRUISING THE PACIFIC OCEAN
CRUISING THE PACIFIC OCEAN
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Day 8 · Puntarenas, Costa Rica
Puntarenas, Costa Rica
Arrive 6:00 am · Depart 7:00 pm
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Day 9 · CRUISING THE PACIFIC OCEAN
CRUISING THE PACIFIC OCEAN
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Day 10 · Puerto Quetzal, Guatemala
Puerto Quetzal, Guatemala
Arrive 7:00 am · Depart 7:00 pm
Puerto Quetzal has become the destination of choice for historians interested in looking at ancient Mayan ruins. The ancient city of Tikal is nearby, and its ruins are remarkably well preserved. Once you've seen the ruins, take it easy along Guatemala's Pacific shore. The beaches here attract Guatemalans from all over the country.
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Day 11 · CRUISING THE PACIFIC OCEAN
CRUISING THE PACIFIC OCEAN
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Day 12 · Acapulco, Mexico
Acapulco, Mexico
Arrive 8:00 am · Depart 5:00 pm
Whitewashed villas ring magnificent Acapulco Bay, forming an unforgettable spectacle. View Mexico's premier Pacific playground from the scenic highway above the harbor, then stop to enjoy Acapulco's most famous attraction: the daredevil cliff-divers of La Quebrada, who pray at a nearby chapel, then plunge from the 130-foot-high cliffs.
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Day 13 · CRUISING THE PACIFIC OCEAN
CRUISING THE PACIFIC OCEAN
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Day 14 · Cabo San Lucas, Mexico
Cabo San Lucas, Mexico
Arrive 10:00 am · Depart 6:00 pm
Sail past Los Arcos, the soaring rock archway at the extreme southern tip of Baja California that guards Cabo's perfect harbor. This idyllic bay once sheltered treasure ships from the Orient, and pirate brigs bent on those treasures. Now Cabo caters to an international vacation set, and has a strong artistic tradition famous for its black-coral jewelry.
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Day 15 · CRUISING THE PACIFIC OCEAN
CRUISING THE PACIFIC OCEAN
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Day 16 · San Diego, California
San Diego, California
Depart 10:00 pm
Blessed with a sunny climate and a fine natural harbor, San Diego has grown from a Spanish mission into a thriving town. With two universities, a world-class zoo and safari park, the famous Hotel Del Coronado and the museums and attractions of Balboa Park, it's well worth exploring.
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Day 17 · Los Angeles, California
Los Angeles, California
Arrive 7:00 am
Sprawling between the mountains and the beaches, Los Angeles is quintessential California. Whether your taste runs to fashionable Beverly Hills, the mega-entertainment of the movie studios, or the sizzle of homestyle Mexican food on Olvera Street, the city of angels is worth exploring.
Route Illustration - Actual route may differ
Highlights
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Sail aboard Seven Seas Grandeur.
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Travel from 2026-12-29 through 2027-01-14.
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Visit Miami, Florida, Georgetown, Grand Cayman, Cayman Islands, Cartagena, Spain, Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Cabo San Lucas, Mexico, San Diego, California, Los Angeles, California.
Recently found pricing
Cabin pricing snapshot
Recent cabin prices we found for this sailing. Pricing is shown per person and may change at any time.
Cabin Types
Inside
Not currently available — cabin inventory may change.
Oceanview
Not currently available — cabin inventory may change.
Balcony
Not currently available — cabin inventory may change.
SuiteRecently found from $16,949 per person
Port charges, taxes, and fees of $1,796 USD included
Final taxes, fees, promotions, or availability can change.
Additional Information
Price, availability, taxes, fees, promotions, occupancy requirements, and final cabin availability can change until booked. When you book travel through a professional travel advisor, suppliers often provide exclusive value-adds, upgrades, and promotions that are unavailable when booking directly online. These unadvertised or agency-exclusive perks vary by vendor and destination.
Gallery
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Route Illustration - Actual route may differ
Tags
allcruisePanama CanalRegent Seven Seas CruisesSeven Seas GrandeurMiami, Florida