22-Night South America Cruise on Seven Seas Grandeur
South America is huge, with scenic wonders that would impress even the most jaded traveler, cosmopolitan cities and native villages, snow-capped mountains, deserts and lush rain forests, miles of sandy beaches and areas so isolated a visitor feels swept back in time. There are many options to cruising South America, and there is no better way to explore this vast continent than on a cruise vacation.
Book with a professional travel advisor and you may unlock more than what appears in a standard online search. Depending on the supplier and trip, your advisor may have access to preferred or agency-negotiated group rates, special promotions, upgrades, onboard or resort credits, and other added-value benefits that are not always available through direct booking.
During our consultation, we may ask for a few details—such as your country or state of residence, ZIP code, age eligibility, military status, past-guest history, or loyalty memberships. These details can help us identify fares and benefits you may qualify for and compare them against publicly available options.
Not every offer applies to every traveler, and availability varies by supplier, destination, sailing, travel dates, and eligibility. But the more we know about your trip and the qualifications that may apply to you, the more thoroughly we can search for opportunities to enhance your vacation and help you secure the best available overall value not just the first price you see online.
Recent price found was as low as: $25,149 per person. Port charges, taxes, and fees of $2,927 USD included
Itinerary Overview
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Day 1 · Panama City, Panama
Panama City, Panama
Depart 5:00 pm
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Day 2 · PANAMA CANAL TRANSIT
PANAMA CANAL TRANSIT
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Day 3 · CRUISING THE CARIBBEAN SEA
CRUISING THE CARIBBEAN SEA
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Day 4 · Oranjestad, Sint Eustatius
Oranjestad, Sint Eustatius
Arrive 10:00 am · Depart 7:00 pm
Welcome to Oranjestad, the charming capital of Sint Eustatius, where history meets natural beauty. This quaint island town boasts beautifully preserved colonial architecture, inviting you to explore its rich heritage. Discover stunning hiking trails that lead to breathtaking views of the Caribbean Sea and the nearby volcanic peak, The Quill. Snorkel in vibrant coral reefs teeming with marine life or relax on serene beaches. With its laid-back atmosphere and friendly locals, Oranjestad offers a perfect escape for travelers seeking a blend of adventure and tranquility in a picturesque setting.
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Day 5 · CRUISING THE CARIBBEAN SEA
CRUISING THE CARIBBEAN SEA
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Day 6 · Port of Spain, Trinidad
Port of Spain, Trinidad
Arrive 7:00 am · Depart 1:00 pm
Steel drums and calypso were born here. Nature lovers will delight in the Asa Wright Nature Center and the Caroni Bird Sanctuary, two of the Caribbean's best known conservation centers.
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Day 7 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 8 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 9 · CRUISING THE AMAZON RIVER
CRUISING THE AMAZON RIVER
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Day 10 · CRUISING THE AMAZON RIVER
CRUISING THE AMAZON RIVER
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Day 11 · Manaus, Brazil
Manaus, Brazil
Arrive 7:00 am
A cultural outpost in the heart of the Amazon rainforest, Manaus was famous for the extravagant lifestyle and architecture of the 19th century rubber barons who made their fortunes here. The renovated opera house stands as an opulent testament to their vast wealth.
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Day 12 · Manaus, Brazil
Manaus, Brazil
Depart 4:00 pm
A cultural outpost in the heart of the Amazon rainforest, Manaus was famous for the extravagant lifestyle and architecture of the 19th century rubber barons who made their fortunes here. The renovated opera house stands as an opulent testament to their vast wealth.
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Day 13 · Boca da Valeria, Brazil
Boca da Valeria, Brazil
Arrive 10:00 am · Depart 5:00 pm
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Day 14 · Alter do Chao, Brazil
Alter do Chao, Brazil
Arrive 7:30 am · Depart 3:00 pm
Turning out of the muddy Amazon, you will cruise into the blue Rio Tapajos, to anchor off the village of Alter do Chao. Here you can tour the Center for Preservation of Indigenous Arts, with displays on the lifestyles of local tribes. Or cross to a white sand beach for a refreshing swim in the clear river waters.
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Day 15 · CRUISING THE AMAZON RIVER
CRUISING THE AMAZON RIVER
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Day 16 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 17 · CRUISING THE ATLANTIC OCEAN
CRUISING THE ATLANTIC OCEAN
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Day 18 · St. Georges, Grenada, West Indies
St. Georges, Grenada, West Indies
Arrive 11:00 am · Depart 6:00 pm
Called the "Spice Island" for its abundance of cinnamon and nutmeg, still sold at the waterfront market, Grenada is spicy in many other ways. St. George's has historic buildings in brick and mellow stone, and one of the loveliest harbors in the Caribbean. The coastline is full of secluded coves, while the mountainous interior is rich in rainforests and frothy rivers.
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Day 19 · CRUISING THE CARIBBEAN SEA
CRUISING THE CARIBBEAN SEA
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Day 20 · Willemstad, Curacao
Willemstad, Curacao
Arrive 7:00 am · Depart 2:00 pm
The ship passes through a channel in the reef, into a broad, perfectly protected natural harbor. This is Willemstad, where Dutch gingerbread houses, superb shopping, excellent restaurants and bustling casinos abound. Nature buffs will love the exotic plants and tropical birdlife of Christoffel National Park. And don''t forget to sample the famous Cura�ao liqueur, still made here.
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Day 21 · CRUISING THE CARIBBEAN SEA
CRUISING THE CARIBBEAN SEA
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Day 22 · PANAMA CANAL TRANSIT
PANAMA CANAL TRANSIT
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Day 23 · Panama City, Panama
Panama City, Panama
Arrive 7:00 am
Route Illustration - Actual route may differ
Highlights
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Sail aboard Seven Seas Grandeur.
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Travel from 2027-03-09 through 2027-03-31.
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Visit Panama City, Panama, Oranjestad, Sint Eustatius, Port of Spain, Trinidad, Manaus, Brazil, Boca da Valeria, Brazil, Alter do Chao, Brazil, St. Georges, Grenada, West Indies, Willemstad, Curacao.
Recently found pricing
Cabin pricing snapshot
Recent cabin prices we found for this sailing. Pricing is shown per person and may change at any time.
Cabin Types
Inside
Not currently available — cabin inventory may change.
Oceanview
Not currently available — cabin inventory may change.
Balcony
Not currently available — cabin inventory may change.
SuiteRecently found from $25,149 per person
Port charges, taxes, and fees of $2,927 USD included
Final taxes, fees, promotions, or availability can change.
Additional Information
Price, availability, taxes, fees, promotions, occupancy requirements, and final cabin availability can change until booked. When you book travel through a professional travel advisor, suppliers often provide exclusive value-adds, upgrades, and promotions that are unavailable when booking directly online. These unadvertised or agency-exclusive perks vary by vendor and destination.
Gallery
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Route Illustration - Actual route may differ
Tags
allcruiseSouth AmericaRegent Seven Seas CruisesSeven Seas GrandeurPanama City, Panama
