South America is huge, with scenic wonders that would impress even the most jaded traveler, cosmopolitan cities and native villages, snow-capped mountains, deserts and lush rain forests, miles of sandy beaches and areas so isolated a visitor feels swept back in time. There are many options to cruising South America, and there is no better way to explore this vast continent than on a cruise vacation.
Book with a professional travel advisor and you may unlock more than what appears in a standard online search. Depending on the supplier and trip, your advisor may have access to preferred or agency-negotiated group rates, special promotions, upgrades, onboard or resort credits, and other added-value benefits that are not always available through direct booking.
During our consultation, we may ask for a few details—such as your country or state of residence, ZIP code, age eligibility, military status, past-guest history, or loyalty memberships. These details can help us identify fares and benefits you may qualify for and compare them against publicly available options.
Not every offer applies to every traveler, and availability varies by supplier, destination, sailing, travel dates, and eligibility. But the more we know about your trip and the qualifications that may apply to you, the more thoroughly we can search for opportunities to enhance your vacation and help you secure the best available overall value not just the first price you see online.
Recent price found was as low as: $1,899 per person. Taxes and fees of $990 USD included. Port charges of $400 USD included.
Itinerary Overview
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Day 1 · Fort Lauderdale (Port Everglades), Florida
Fort Lauderdale (Port Everglades), Florida
Depart 5:00 pm
Originally a fort built by the U.S. Army in 1838 during the Second Seminole War, Fort Lauderdale welcomes visitors with broad, palm-fringed beaches and an easy pace of life. Stroll along fashionable Las Olas Boulevard with its stylish shops or enjoy a sightseeing cruise through the city''s canals, boasting more waterways than Venice. Or, venture out and explore the cosmopolitan city of Palm Beach, or the wildlife sanctuary of the Everglades.
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Day 2 · AT SEA
AT SEA
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Day 3 · Georgetown, Grand Cayman, Cayman Islands
Georgetown, Grand Cayman, Cayman Islands
Arrive 10:00 am · Depart 6:00 pm
Survey the neatly shuttered shops for bargains, or the twisted rock formations known as "Hell." But there's nothing hellish about the white-sand heaven of Seven Mile Beach. Sample the rum distilled here and be sure to visit the world's only sea turtle farm.
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Day 4 · AT SEA
AT SEA
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Day 5 · Panama Canal, Panama
Panama Canal, Panama
Arrive 6:00 am · Depart 6:00 am
Spend an unforgettable day cruising the Panama Canal, a fifty-one-mile waterway through the rainforest that is one of the world's engineering masterpieces. The ship glides down the canal with inches to spare, through locks that raise and lower it like a toy. Along the way it crosses enormous Gatun Lake, and the amazing Gaillard Cut, blasted out of a solid mountainside.
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Day 5 · Panama Canal, Panama
Panama Canal, Panama
Spend an unforgettable day cruising the Panama Canal, a fifty-one-mile waterway through the rainforest that is one of the world's engineering masterpieces. The ship glides down the canal with inches to spare, through locks that raise and lower it like a toy. Along the way it crosses enormous Gatun Lake, and the amazing Gaillard Cut, blasted out of a solid mountainside.
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Day 5 · Panama Canal, Panama
Panama Canal, Panama
Arrive 8:00 pm · Depart 8:00 pm
Spend an unforgettable day cruising the Panama Canal, a fifty-one-mile waterway through the rainforest that is one of the world's engineering masterpieces. The ship glides down the canal with inches to spare, through locks that raise and lower it like a toy. Along the way it crosses enormous Gatun Lake, and the amazing Gaillard Cut, blasted out of a solid mountainside.
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Day 5 · Fuerte Amador, Panama
Fuerte Amador, Panama
Arrive 9:00 pm
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Day 6 · Fuerte Amador, Panama
Fuerte Amador, Panama
Depart 4:00 pm
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Day 7 · CROSSING THE EQUATOR (CRUISING ONLY)
CROSSING THE EQUATOR (CRUISING ONLY)
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Day 8 · Manta (Quito), Ecuador
Manta (Quito), Ecuador
Arrive 4:00 am · Depart 8:00 pm
...The port of Manta is the busiest fishing port on earth.The Museo del Banco Central is a fantastic museum ...Manta's beaches are spacious as well as beautiful, and are home to a wide array of wildlife.There are a few truly great restaurants in Manta, and the nightlife is fantastic.
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Day 9 · AT SEA
AT SEA
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Day 10 · Salaverry (Trujillo), Peru
Salaverry (Trujillo), Peru
Arrive 8:00 am · Depart 5:00 pm
This is the port for Trujillo, the "Lordly City," whose elegant mansions and churches reflect the aristocracy of the Spanish colonial era. Here you may opt for a thrilling excursion to Chan-Chan, an immense and magnificent enclave that since A.D. 1300 has been the center of the sophisticated Chim culture.
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Day 11 · Callao (Lima), Peru
Callao (Lima), Peru
Arrive 10:00 am
Callao is your port of entry to the glittering, elegant city of Lima, the darling of Peru. Founded by Pizarro and the Conquistadors, the capital city today offers priceless collections ranging from the Museum of Gold to the Museum of Anthropology and Archeology. Pizarro's remains can be found in the Cathedral, built in 1746. From Lima, you can also take a tour to Machu Picchu, the mysterious lost city of the Incas high in the Andes, or to Cuzco, the capital of the Incan Empire.
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Day 12 · Callao (Lima), Peru
Callao (Lima), Peru
Depart 6:00 pm
Callao is your port of entry to the glittering, elegant city of Lima, the darling of Peru. Founded by Pizarro and the Conquistadors, the capital city today offers priceless collections ranging from the Museum of Gold to the Museum of Anthropology and Archeology. Pizarro's remains can be found in the Cathedral, built in 1746. From Lima, you can also take a tour to Machu Picchu, the mysterious lost city of the Incas high in the Andes, or to Cuzco, the capital of the Incan Empire.
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Day 13 · General San Martin, Peru
General San Martin, Peru
Arrive 7:00 am · Depart 6:00 pm
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Day 14 · AT SEA
AT SEA
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Day 15 · AT SEA
AT SEA
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Day 16 · Coquimbo (La Serena), Chile
Coquimbo (La Serena), Chile
Arrive 8:00 am · Depart 4:00 pm
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Day 17 · San Antonio, Santiago, Chile
San Antonio, Santiago, Chile
Arrive 7:00 am
Route Illustration - Actual route may differ
Highlights
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Sail aboard Oosterdam.
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Travel from 2026-11-18 through 2026-12-04.
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Visit Fort Lauderdale (Port Everglades), Florida, Georgetown, Grand Cayman, Cayman Islands, Panama Canal, Panama, Fuerte Amador, Panama, Manta (Quito), Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin, Peru, Coquimbo (La Serena), Chile, San Antonio, Santiago, Chile.
Recently found pricing
Cabin pricing snapshot
Recent cabin prices we found for this sailing. Pricing is shown per person and may change at any time.
Cabin Types
InsideRecently found from $1,899 per person
Taxes and fees of $990 USD included. Port charges of $400 USD included.
OceanviewRecently found from $1,949 per person
Taxes and fees of $990 USD included. Port charges of $400 USD included.
BalconyRecently found from $2,799 per person
Taxes and fees of $990 USD included. Port charges of $400 USD included.
SuiteRecently found from $4,299 per person
Taxes and fees of $990 USD included. Port charges of $400 USD included.
Final taxes, fees, promotions, or availability can change.
Additional Information
Price, availability, taxes, fees, promotions, occupancy requirements, and final cabin availability can change until booked. When you book travel through a professional travel advisor, suppliers often provide exclusive value-adds, upgrades, and promotions that are unavailable when booking directly online. These unadvertised or agency-exclusive perks vary by vendor and destination.
Gallery
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Route Illustration - Actual route may differ
Tags
allcruiseSouth AmericaHolland America LineOosterdamFort Lauderdale (Port Everglades), Florida
