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Route Illustration - Actual route may differ
Cruise

16-Night Panama Canal Cruise on Nieuw Amsterdam

Slice through Central America via the most famous canal in the world. With more than 900 species of birds, 10,000 species of plants, 1,350 plants and animals indigenous to the country and more species of mammals and amphibians than any other Central American country, Panama has one of the richest tropical environments on earth. Follow the footsteps of the conquistadors and immerse yourself in Panama's rich ecological and cultural diversity.
As low as $1,899 per person
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Rachael Roberts
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Departure Port

  • San Diego, California

Debarkation Port

  • Fort Lauderdale (Port Everglades), Florida

Destination

  • Panama Canal

Voyage at a glance

16-night European sailing aboard Nieuw Amsterdam.

ShipNieuw Amsterdam
Sailing datesFriday, October 2, 2026 – Sunday, October 18, 2026
RouteSan Diego, California → Fort Lauderdale (Port Everglades), Florida
Recently found from$1,899 per person

Advisor Consultation

Get personalized guidance and book your trip with confidence.

Schedule My Consultation

Book with a professional travel advisor and you may unlock more than what appears in a standard online search. Depending on the supplier and trip, your advisor may have access to preferred or agency-negotiated group rates, special promotions, upgrades, onboard or resort credits, and other added-value benefits that are not always available through direct booking.

During our consultation, we may ask for a few details—such as your country or state of residence, ZIP code, age eligibility, military status, past-guest history, or loyalty memberships. These details can help us identify fares and benefits you may qualify for and compare them against publicly available options.

Not every offer applies to every traveler, and availability varies by supplier, destination, sailing, travel dates, and eligibility. But the more we know about your trip and the qualifications that may apply to you, the more thoroughly we can search for opportunities to enhance your vacation and help you secure the best available overall value not just the first price you see online.

Recent price found was as low as: $1,899 per person. Taxes and fees of $700 USD included. Port charges of $400 USD included.

Itinerary Overview

Day 1 · San Diego, California

San Diego, California

Depart 4:00 pm

Blessed with a sunny climate and a fine natural harbor, San Diego has grown from a Spanish mission into a thriving town. With two universities, a world-class zoo and safari park, the famous Hotel Del Coronado and the museums and attractions of Balboa Park, it's well worth exploring.

Day 2 · AT SEA

AT SEA

Day 3 · AT SEA

AT SEA

Day 4 · Puerto Vallarta, Mexico

Puerto Vallarta, Mexico

Arrive 8:00 am · Depart 5:00 pm

Hollywood discovered this little fishing village back in the 1960's, and since then luxury resorts and bougainvillea-covered villas have flourished in the delightful seaside climate. Yet hints of past tranquility remain: cobbled courtyards where the locals hold their markets, and superb sport-fishing just offshore.

Day 5 · AT SEA

AT SEA

Day 6 · Huatulco, Mexico

Huatulco, Mexico

Arrive 10:00 am · Depart 5:00 pm

The entire community is, in essence, a beach, so you will never be far from the sparkling sea and the warm, shimmering sand.There are a couple of outstanding restaurants in the vicinity, and the shopping here is limited but still enjoyable.The Museo de Artesanias Oxaquenas is an extraordinary museum where you can watch artistic geniuses at work.

Day 7 · Puerto Chiapas, Mexico

Puerto Chiapas, Mexico

Arrive 8:00 am · Depart 5:00 pm

Day 8 · Puerto Quetzal, Guatemala

Puerto Quetzal, Guatemala

Arrive 6:00 am · Depart 8:00 pm

Puerto Quetzal has become the destination of choice for historians interested in looking at ancient Mayan ruins. The ancient city of Tikal is nearby, and its ruins are remarkably well preserved. Once you've seen the ruins, take it easy along Guatemala's Pacific shore. The beaches here attract Guatemalans from all over the country.

Day 9 · Acajutla, El Salvador

Acajutla, El Salvador

Arrive 7:00 am · Depart 5:00 pm

Day 10 · AT SEA

AT SEA

Day 11 · AT SEA

AT SEA

Day 12 · Panama Canal, Panama

Panama Canal, Panama

Arrive 5:00 am · Depart 5:00 am

Spend an unforgettable day cruising the Panama Canal, a fifty-one-mile waterway through the rainforest that is one of the world's engineering masterpieces. The ship glides down the canal with inches to spare, through locks that raise and lower it like a toy. Along the way it crosses enormous Gatun Lake, and the amazing Gaillard Cut, blasted out of a solid mountainside.

Day 12 · Panama Canal, Panama

Panama Canal, Panama

Spend an unforgettable day cruising the Panama Canal, a fifty-one-mile waterway through the rainforest that is one of the world's engineering masterpieces. The ship glides down the canal with inches to spare, through locks that raise and lower it like a toy. Along the way it crosses enormous Gatun Lake, and the amazing Gaillard Cut, blasted out of a solid mountainside.

Day 12 · Panama Canal, Panama

Panama Canal, Panama

Arrive 7:00 pm · Depart 7:00 pm

Spend an unforgettable day cruising the Panama Canal, a fifty-one-mile waterway through the rainforest that is one of the world's engineering masterpieces. The ship glides down the canal with inches to spare, through locks that raise and lower it like a toy. Along the way it crosses enormous Gatun Lake, and the amazing Gaillard Cut, blasted out of a solid mountainside.

Day 13 · Cartagena, Colombia

Cartagena, Colombia

Arrive 12:00 pm · Depart 6:00 pm

Charming Cartagena is one of the most fascinating towns in South America. The old city, almost completely surrounded by lagoons, bays and the Caribbean Sea, is still girded by its 17th-century fortifications. Once these guarded the gold and treasures of the New World, bound for Spain; now they shelter ornate churches and convents, the dramatic Palace of the Inquisition, and other historic gems.

Day 14 · AT SEA

AT SEA

Day 15 · AT SEA

AT SEA

Day 16 · Half Moon Cay (Little San Salvador Island), Bahama

Half Moon Cay (Little San Salvador Island), Bahama

Arrive 8:00 am · Depart 2:00 pm

Half Moon Cay has the attraction of other private islands plus some! This 2500 acre island, prides itself in maintaining the natural ecology; it protects 2400 of its acres by keeping them wholly unspoiled. Located one hundred miles SE of Nassau, its large protected bay used to be a famous refuge for pirates (or as famous as a pirate refuge can get). Enjoy nature activities, beach fun, or just swing in the hammock to the island steel band. Make sure to take at least one dip in the beach which is only chest deep 60 ft out!

Day 17 · Fort Lauderdale (Port Everglades), Florida

Fort Lauderdale (Port Everglades), Florida

Arrive 7:00 am

Originally a fort built by the U.S. Army in 1838 during the Second Seminole War, Fort Lauderdale welcomes visitors with broad, palm-fringed beaches and an easy pace of life. Stroll along fashionable Las Olas Boulevard with its stylish shops or enjoy a sightseeing cruise through the city''s canals, boasting more waterways than Venice. Or, venture out and explore the cosmopolitan city of Palm Beach, or the wildlife sanctuary of the Everglades.

Route Illustration - Actual route may differ
Route Illustration - Actual route may differ

Highlights

Sail aboard Nieuw Amsterdam.
Travel from 2026-10-02 through 2026-10-18.
Visit San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Panama Canal, Panama, Cartagena, Colombia, Half Moon Cay (Little San Salvador Island), Bahama, Fort Lauderdale (Port Everglades), Florida.
Recently found pricing

Cabin pricing snapshot

Recent cabin prices we found for this sailing. Pricing is shown per person and may change at any time.

Cabin Types
  • InsideRecently found from $1,899 per person
    Taxes and fees of $700 USD included. Port charges of $400 USD included.
  • OceanviewRecently found from $1,979 per person
    Taxes and fees of $700 USD included. Port charges of $400 USD included.
  • BalconyRecently found from $2,199 per person
    Taxes and fees of $700 USD included. Port charges of $400 USD included.
  • Suite
    Not currently available — cabin inventory may change.

Final taxes, fees, promotions, or availability can change.

Additional Information

Price, availability, taxes, fees, promotions, occupancy requirements, and final cabin availability can change until booked. When you book travel through a professional travel advisor, suppliers often provide exclusive value-adds, upgrades, and promotions that are unavailable when booking directly online. These unadvertised or agency-exclusive perks vary by vendor and destination.

Tags

allcruisePanama CanalHolland America LineNieuw AmsterdamSan Diego, California